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research Obesity resistance of the stearoyl-CoA desaturase-deficient (scd1 ^-/-) mouse results from disruption of the epidermal lipid barrier and adaptive thermoregulation

87 citations , March 2007 in “Biological Chemistry”

Deleting the scd1 gene in mice prevents obesity by disrupting skin lipids and improving heat regulation.

research Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction

87 citations , July 2009 in “Journal of Cell Science”

Deleting the CDSN gene causes severe skin and hair problems, leading to death.

research Aging Skin: A Window to the Body

1 citations , April 2016 in “CRC Press eBooks”

Skin aging reflects overall body aging and can indicate internal health conditions.

Stem Cells Behind the Barrier: Mechanisms Regulating Epidermal Stem and Progenitor Cell Differentiation

research Stem Cells behind the Barrier

22 citations , June 2013 in “International journal of molecular sciences”

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

research Epidermal Vascular Endothelial Growth Factor Production Is Required for Permeability Barrier Homeostasis, Dermal Angiogenesis, and the Development of Epidermal Hyperplasia

100 citations , August 2008 in “American Journal Of Pathology”

VEGF-A is crucial for normal skin function and may be linked to psoriasis.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 443 upvotes 6 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

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learn Epidermal Growth Factor

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