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2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

research 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

86 citations , August 2011 in “Toxicological sciences”

TCDD speeds up skin barrier formation by increasing certain gene expressions.

LSD1 Is Critical for Epidermal Development and Skin Barrier Formation

research 1397 LSD1 is critical for epidermal development and skin barrier formation

April 2023 in “Journal of Investigative Dermatology”

LSD1 is essential for healthy skin development and creating the skin's protective barrier.

research O05 Distinct epidermal cell populations and single-cell gene expression signatures are associated with Staphylococcus aureus in atopic dermatitis

January 2026 in “British Journal of Dermatology”

Staphylococcus aureus affects immune responses and skin cells in atopic dermatitis, suggesting new treatment targets.

research Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction

87 citations , July 2009 in “Journal of Cell Science”

Deleting the CDSN gene causes severe skin and hair problems, leading to death.

research The role of Glucosylceramides in Keratinocyte Differentiation and Epidermal Barrier Function

1 citations , January 2013

Glucosylceramides are essential for healthy skin and proper wound healing.

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Learn

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learn Epidermal Growth Factor

learn Thymosin Beta 4

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Community Join

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community Keratin microspheres - breakthrough

in Research/Science 15 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community A Theory on Why Microneedling Works

173 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

community Why nobody uses 0.25% (2.5mg/ml)?

in Treatment 66 upvotes 2 years ago

The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 246 upvotes 4 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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Experts

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Clinics

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