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GlossaryEpidermal Necrosis

death of outer skin cells causing discoloration and peeling

Epidermal necrosis refers to the death of cells in the outermost layer of the skin, known as the epidermis. This condition can result from various causes, including severe infections, burns, or adverse reactions to medications, leading to symptoms like skin discoloration, blistering, and peeling. For professionals, it is crucial to identify the underlying cause to provide appropriate treatment and prevent further tissue damage.

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research Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice

53 citations , July 2009 in “Cancer Research”

Blocking certain proteins can reduce skin inflammation caused by cancer treatment.

research Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice

March 2023

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

research Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice

March 2023

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

research Fatal Toxic Epidermal Necrolysis Associated With Cetuximab in a Patient With Colon Cancer

35 citations , May 2008 in “Journal of Clinical Oncology”

A cancer patient died from a severe skin reaction after taking the drug cetuximab.

research Toxic epidermal necrolysis caused by etonogestrel implantation: A rare presentation

1 citations , June 2022 in “JAAD case reports”

A woman developed a severe skin reaction after getting a birth control implant.

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community How to take care of the microneedler?

in Microneedling 7 upvotes 11 months ago

Disinfecting microneedlers is important to prevent infection, with suggestions to use high-percentage alcohol or denture tablets for sterilization. Rollers may cause skin damage, so stamps or pens are recommended for safer microneedling.

community 2 years fin only 1mg/daily + 4 months of gradually introducing Dut 0.5mg/daily

in Progress Pictures 1708 upvotes 10 months ago

A user experienced significant hair regrowth using finasteride 1 mg daily for two years and gradually introduced dutasteride 0.5 mg daily over four months. They reported no side effects and plan to switch fully to dutasteride due to its cost-effectiveness and potential effectiveness.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Does applying Epidermal Growth Factor (EGF) make a difference in hair growth?

in Treatment 4 upvotes 3 years ago

Applying Epidermal Growth Factor (EGF) topically may improve skin and potentially promote scalp health and hair growth, especially after microneedling. The user shares their positive experience with EGF and provides a product link.

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learn Epidermal Growth Factor

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