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research MLPH-mediated activation of dermal papilla IGF-1 signaling drives human hair shaft elongation and anagen induction

February 2026 in “Biomedicine & Pharmacotherapy”

MLPH helps hair grow by activating IGF-1 signaling in hair cells.

research Human hair follicles are an extrarenal source and a nonhematopoietic target of erythropoietin

71 citations , May 2007 in “The FASEB journal”

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

research Transcriptome Sequencing Reveals Differences between Primary and Secondary Hair Follicle-derived Dermal Papilla Cells of the Cashmere Goat (Capra hircus)

81 citations , September 2013 in “PLoS ONE”

Primary and secondary hair follicle cells in Cashmere goats have different gene expressions affecting hair growth and size.

research Editorial highlights

October 2024 in “Developmental Dynamics”

Recent advances show zebrafish can model anemia, Alx4 affects craniofacial and hair development, and mTORC1 is crucial for retinal development.

Skin Regeneration with Conical and Hair Follicle Structure of Deep Second-Degree Scalding Injuries via Combined Expression of the EPO Receptor and Beta Common Receptor by Local Subcutaneous Injection of Nanosized rhEPO

research Skin regeneration with conical and hair follicle structure of deep second-degree scalding injuries via combined expression of the EPO receptor and beta common receptor by local subcutaneous injection of nanosized rhEPO

15 citations , March 2012 in “International journal of nanomedicine”

Local injections of nanosized rhEPO can speed up skin healing and improve quality after deep second-degree burns.

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community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 39 upvotes 3 years ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

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