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research Randomized clinical trial of astaxanthin supplement on serum inflammatory markers and ER stress‐apoptosis gene expression in PBMCs of women with PCOS

19 citations , July 2024 in “Journal of Cellular and Molecular Medicine”

Astaxanthin may reduce inflammation in women with PCOS, but doesn't significantly improve symptoms.

Repurposing a Clinical Antimalarial for the Therapeutic Induction of Lethal ER Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma

research 554 Repurposing a clinical antimalarial for the therapeutic induction of lethal ER stress targeting BRAF-kinase inhibitor-resistant malignant melanoma

April 2016 in “Journal of Investigative Dermatology”

Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.

research Endoplasmic reticulum stress at the crossroads of progeria and atherosclerosis

11 citations , March 2019 in “EMBO molecular medicine”

A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.

Connection Between Granulosa Cell Pyroptosis and Oocyte Endoplasmic Reticulum Stress in a Mouse Model of Polycystic Ovary Syndrome

research Connection between granulosa cell pyroptosis and oocyte endoplasmic reticulum stress in a mouse model of polycystic ovary syndrome

2 citations , November 2025 in “Journal of Ovarian Research”

Reducing granulosa cell pyroptosis may improve oocyte maturation in PCOS.

research Role of epigallocatechin-3-gallate from green tea in iron chelation and endoplasmic reticulum stress pathway in colorectal cancer cells

December 2018

Green tea compound EGCG could potentially treat colorectal cancer by removing iron and causing stress in cancer cells leading to their death.

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Community Join

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community Oral Minoxidil- Be Careful!!!!!

in Minoxidil 417 upvotes 1 year ago

Oral minoxidil can cause severe side effects, including heart issues, even at low doses. Users suggest starting with a lower dose or using topical treatments to minimize risks.

community Could fatty liver(other issues related to it..)play a role in Dupa/Aga?

in Treatment 7 upvotes 1 year ago

Fatty liver and related issues may influence hair loss conditions like Dupa/Aga. Treatments discussed include Minoxidil, finasteride, RU58841, myo-inositol, and L-glutamine.

community Why the fu*k do people behave like this?

in Chat 385 upvotes 3 years ago

People making comments on others' hair loss, and the different strategies used to deal with it. Treatments mentioned include finasteride and minoxidil.

community Serious Oral Minoxidil Side Effects

in Minoxidil 30 upvotes 5 years ago

A user experienced severe side effects, including heart-related symptoms, after increasing their oral minoxidil dosage to 5 mg, leading them to stop the medication and seek medical advice. Many users advised against high doses of oral minoxidil, suggesting anxiety as a possible cause, and recommended consulting a doctor or switching to topical treatments.

community DHT Isn't (Directly) Important

in Research/Science 103 upvotes 1 year ago

Finasteride's potential side effects, especially sexual dysfunction, are discussed, with emphasis on hormonal balance between testosterone and estradiol. Users share experiences with finasteride, minoxidil, and dutasteride, highlighting the variability in side effects and the influence of mindset and lifestyle.

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