learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
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5 / 801 resultslearn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
learn Azelaic Acid
acid used for antimicrobial, anti-inflammatory and anti-androgenic properties
learn dl-alpha-tocopherol
learn GT20029
research compound made to degrade androgen receptors in scalp
Research
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research Minoxidil May be a Partial Agonist of Estrogen Receptor Alpha
Minoxidil might partially activate estrogen receptors, affecting hair growth.
research Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor (ER)-α Is Checked by ERβ Signaling
Estrogen receptors affect hair growth, with ER beta slowing down the hair cycle changes caused by ER alpha.
research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An in Silico and in Vitro Study
Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
research 556 α 1 -AR agonist induced piloerection protects against the development of traction alopecia
Phenylephrine may help prevent hair loss from pulling on the hair roots.
research 25 years of ERβ: a personal journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
Community Join
5 / 1000+ resultscommunity Why is Kevin Mann (Haircafe) Hated?
Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.
community Would there be ANY reason to still take 5AR inhibitors if pyrilutamide does what is intended?
A potential new treatment for hair loss, Pyrilutamide, and the discussion of whether or not people should still be taking traditional treatments like Minoxidil and Finasteride with it.
community Finasteride vs Dutasteride: The Science
The conversation compares Finasteride and Dutasteride for hair loss treatment, discussing their effectiveness and side effects. Users share personal results and consider combining treatments like Dutasteride with RU58841.
community DHT is NOT very important for adults, is it?
A user experienced negative side effects, including low libido and lack of motivation, after using finasteride for hair loss and felt better after stopping it. Others shared similar experiences with finasteride and dutasteride, while some reported no side effects, showing varied individual responses.
community Mechanism of action of alfatradiol (17 alpha estradiol)
The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.