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    GlossaryEpidermal Permeability Barrier

    outermost skin layer preventing water loss and blocking pathogens

    The Epidermal Permeability Barrier is a critical function of the outermost layer of the skin, known as the stratum corneum. It prevents excessive water loss from the body and protects against the entry of harmful substances and microorganisms. This barrier is maintained by a complex mixture of lipids, proteins, and other molecules that work together to keep the skin hydrated and intact.

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