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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

    Research

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      Inflammatory and Non-Melanocytic Tumoral Pathology of the Nail

      research Inflammatory and non-melanocytic tumoral pathology of the nail

      January 2014 in “Pathology”
      The document concludes that understanding nail anatomy is key for diagnosing nail diseases, early signs of nail melanoma may allow for less aggressive treatment, and specific genetic mutations are important in thyroid cancer prognosis and treatment.
      Genetics of Thyroid Lesions Updated

      research Genetics of thyroid lesions updated

      January 2014 in “Pathology”
      RET mutation is important in familial medullary thyroid carcinoma, and BRAF mutation in papillary thyroid carcinoma is linked to more aggressive cancer and higher death rates.
      Endocrinology

      research Endocrinology

      April 2023 in “Clinical Chemistry and Laboratory Medicine”
      The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

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