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research Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress

88 citations , August 2014 in “PLOS genetics”

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men

31 citations , January 2017 in “Advances in Experimental Medicine and Biology”

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

research Rodent models in placental research. Implications for fetal origins of adult disease

7 citations , January 2022 in “Animal Reproduction”

Using rodents for research shows that health problems in the womb can cause diseases later in life.

research Parameters of obesity in polycystic ovary syndrome

1 citations , January 2017 in “Journal of rare disease research & treatment”

Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.

research 1329 Transglutaminase 2 deficiency leads to lipid accumulation and reduced autophagy in SZ95 sebocytes

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

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community Duasteride and breast tissue accumulation.

in Finasteride/Dutasteride 4 upvotes 5 months ago

The user is experiencing breast tissue growth from taking dutasteride and minoxidil, and is considering reducing the dosage or stopping the medication. Suggestions include seeing an endocrinologist, using Raloxifene or Arimidex, and considering topical treatments or surgery if necessary.

community Anyone experienced weight gain on dutasteride?

in Finasteride/Dutasteride 5 upvotes 4 years ago

Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.

community My experience with dutasteride 4.5 months and oral minoxidil 1.5 months so far

in Finasteride/Dutasteride 10 upvotes 5 years ago

The user switched from finasteride to dutasteride and added oral minoxidil, which helped regrow their hairline and reduce shedding. They experienced side effects like brain fog, sluggishness, and fat gain with dutasteride, and slight chest tightness with oral minoxidil.

community You NEED this if You’re Taking Fin/Dut

in Finasteride/Dutasteride 1 year ago

DIM is suggested to help with estrogen metabolism for those on finasteride or dutasteride, potentially reversing side effects like fat gain and mood changes. Some users doubt its effectiveness, recommending lifestyle changes or consulting a doctor instead.

community 22M High Estrogen after blood test

in Finasteride/Dutasteride 1 upvotes 5 months ago

A 22-year-old male with high estrogen levels is considering finasteride for hair loss but is concerned about potential side effects due to his hormone levels and family history of diabetes. Users suggest consulting a doctor, possibly an endocrinologist, and considering lifestyle changes like diet and exercise to address visceral fat and insulin resistance before starting treatment.

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