Processed fat, SVF, and PRP are safe and effective for facial rejuvenation and hair growth.
June 2026 in “Frontiers in Cell and Developmental Biology” Autologous fat grafting is popular in reconstructive and aesthetic surgery but faces challenges due to unpredictable graft resorption. Two cell-based approaches, stromal vascular fraction (SVF) and culture-expanded adipose-derived stem/stromal cells (ADSCs), have been developed to improve fat retention. Meta-analyses indicate that expanded ADSCs offer significantly better outcomes than SVF, due to their ability to support graft survival through growth factor secretion, immunomodulation, and other mechanisms. The review covers clinical evidence for ADSC- and SVF-enriched fat grafting across various applications, evaluates adjunctive strategies like platelet-rich plasma and exosome-based therapies, and highlights ongoing challenges such as the need for standardized preparation methods and safety assessments.
January 2026 in “The Operating Room Global Journal” Imaging-guided techniques improve safety and outcomes in regenerative aesthetics, but more research is needed for standardized guidelines.
4 citations
,
July 2023 in “Experimental Dermatology” Fat grafting reduces scar fibrosis but may slow skin healing.
60 citations
,
June 2019 in “Ageing Research Reviews” Fat from the body can help improve hair growth and scars when used in skin treatments.