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GlossaryFibroblast Growth Factor Receptor 2

protein involved in cell growth and tissue repair

Fibroblast Growth Factor Receptor 2 (FGFR2) is a protein that plays a crucial role in cell growth, differentiation, and tissue repair. It is particularly important in the development of bones and skin, and mutations in the FGFR2 gene can lead to various developmental disorders and contribute to conditions like craniosynostosis and certain cancers.

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research Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction

119 citations , November 2014 in “Trends in Cell Biology”

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

research An epidermis‐permeable dipeptide is a potential cosmetic ingredient with partial agonist/antagonist activity toward fibroblast growth factor receptors

3 citations , May 2019 in “Journal of Cosmetic Dermatology”

Pro-Ile could be used in cosmetics to improve skin, hair growth, and healing.

research The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development

125 citations , February 2007 in “The EMBO Journal”

Fgfr2b helps maintain healthy skin and prevent cancer.

Antisense Oligonucleotide Targeting Fibroblast Growth Factor Receptor-1 Stimulates Cellular Activity of Hair Follicles in an In Vitro Organ Culture System

research Antisense oligonucleotide targeting fibroblast growth factor receptor (FGFR)-1 stimulates cellular activity of hair follicles in anin vitroorgan culture system

7 citations , March 2007 in “International Journal of Dermatology”

Targeting FGFR-1 with antisense oligonucleotides may help treat baldness by increasing hair follicle activity.

research Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells

66 citations , February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.

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learn Epidermal Growth Factor

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hormone commonly taken for sleep aid has some topical benefits for hair

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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community Serum based on plant extracts boosts hair growth in weeks.

in Treatment 44 upvotes 9 months ago

A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

in Research/Science 126 upvotes 3 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community Alright boys, who’s willing to burn their scalp for science?

in Research/Science 765 upvotes 3 years ago

Researching the effects of scalp trauma on hair growth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.

community Breezula phase 3 results said to be released next month

in Product 27 upvotes 1 year ago

Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 4 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

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