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research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model

13 citations , January 2022 in “Stem cell reviews and reports”

Mouse stem cells from hair follicles can improve wound healing and reduce scarring.

research Beyond scarring: immune-epithelial crosstalk in wound-induced hair follicle neogenesis

July 2026 in “Frontiers in Immunology”

New hair follicles can form in wounds through immune and skin cell interactions, offering potential treatments for hair loss and scarless healing.

research Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

research Hair Follicle Biology, the Sebaceous Gland, and Scarring Alopecias

57 citations , August 1999 in “Archives of dermatology”

Hair follicles grow hair and release it through the skin.

research Hair follicle stem cells in the pathogenesis of the scarring process in cutaneous lupus erythematosus

31 citations , January 2009 in “Autoimmunity Reviews”

Damage to hair follicle stem cells causes permanent hair loss and scarring in cutaneous lupus erythematosus.

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community Verteporfin to deminiaturize follicles

in Research/Science 8 upvotes 3 years ago

User discusses verteporfin for hair regrowth through "super microneedling" and preventing scarring. They mention a case of an old man regrowing hair after a head injury and suggest verteporfin could recreate this result.

community So did the experiments with verteporfin for hair transplant scarring regrowth fall through?

in Transplants 13 upvotes 1 year ago

Verteporfin reduces scar tissue in hair transplants but doesn't significantly regrow hair follicles. More testing is needed to determine its effectiveness.

community Topical Metformin for Hair Transplant donor area skin/hair regeneration?

in Research/Science 4 upvotes 1 year ago

Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.

community Has anyone asked a hair transplant surgeon to consider using verteporfin during their surgery?

in Research/Science 8 upvotes 3 years ago

Exploring the potential of using verteporfin during hair transplants to minimize scarring and regenerate follicles, as well as discussing a possible standardized protocol for this treatment.

community Quote from Pelage (PP-405) Spokesperson...

in Research/Science 122 upvotes 9 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

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