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Research

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research Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis

10 citations , January 2004 in “Dermatologic Surgery”

Storing hair follicles in special buffers with added protective substances can increase hair growth and reduce cell death.

research Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice

173 citations , September 2011 in “Journal of Investigative Dermatology”

IL-6 contributes to hair loss by shortening the growth phase and causing hair follicles to regress.

research 6-Gingerol Inhibits Hair Shaft Growth in Cultured Human Hair Follicles and Modulates Hair Growth in Mice

17 citations , February 2013 in “PLOS ONE”

6-Gingerol, found in ginger, may slow down hair growth and could be used for hair removal.

research Alterations in Hair Follicle Morphology and Hair Shaft Production After Follicular Unit Transplantation

8 citations , February 2016 in “The American Journal of Dermatopathology”

Hair transplants can make hair follicles larger and hair shafts thicker.

research Extensive Hair Shaft Growth after Mouse Whisker Follicle Isolation, Cryopreservation and Transplantation in Nude Mice

7 citations , December 2015 in “PloS one”

Cryopreserved mouse whisker follicles can grow hair when transplanted into nude mice.

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community Microneedling must reach the stem cells in the upper hair shaft

in Treatment 80 upvotes 4 years ago

Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.

community How a follicle next to it is so genetically different that it never miniaturized??

in Chat 219 upvotes 10 months ago

Genetic differences in hair follicles affect hair loss patterns. Treatments discussed include finasteride, dutasteride, minoxidil, and RU58841.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

in Research/Science 66 upvotes 9 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.

in Research/Science 41 upvotes 2 years ago

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

community Reminder: NURTURE those dormant hair follicles for as long as you can until PP405 comes out in 2028-2030

in Treatment 191 upvotes 8 months ago

PP405 is anticipated as a future treatment for dormant hair follicles, but its effectiveness and safety are uncertain. Current treatments include oral minoxidil and microneedling, with some avoiding finasteride due to side effects.

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