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      The Transverse Anatomy of Androgenic Alopecia

      research The Transverse Anatomy of Androgenic Alopecia

      42 citations , December 1990 in “The Journal of Dermatologic Surgery and Oncology”
      The study found that horizontal sections of scalp biopsies are better for analyzing hair loss, showing fewer hairs and more fine hairs in balding areas.
      Spatiotemporal Secondary Hair Follicle Development in the Lanyu Pig: A Novel Pelage Hair Follicle Model

      research Spatiotemporal secondary hair follicle development in the Lanyu pig (Sus scrofa taivanus): a novel pelage hair follicle model

      April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)”
      The study characterizes the secondary hair follicle development in the Lanyu pig, an indigenous breed that retains vellus-like hair follicles, making it a promising model for studying skin regeneration. Unlike commonly used animal models, the Lanyu pig's skin closely resembles human skin, with both primary and secondary hair follicles. The research identified distinct stages of secondary follicle morphogenesis and demonstrated similarities in keratin expression and follicular architecture to human vellus hair follicles. The retention of secondary follicles into adulthood and their autosomal dominant inheritance pattern further support the Lanyu pig's relevance for translational research in human wound healing.
      Inflammatory and Non-Melanocytic Tumoral Pathology of the Nail

      research Inflammatory and non-melanocytic tumoral pathology of the nail

      January 2014 in “Pathology”
      The document concludes that understanding nail anatomy is key for diagnosing nail diseases, early signs of nail melanoma may allow for less aggressive treatment, and specific genetic mutations are important in thyroid cancer prognosis and treatment.

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      community Verteporfin and Microneedling

      in Treatments 1 year ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Journey against alopecia - Finasteride 3 month

      in Progress Pictures  18 upvotes 4 years ago
      A 26-year-old man from France started experiencing hair loss in September 2020 and began using finasteride in June 2021, reporting some improvement after three months without side effects. He plans to continue finasteride for a year before considering additional treatments like minoxidil or dermarolling.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  122 upvotes 6 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community JXL082 is not PP405 and Everychem followed the wrong lead

      in Research/Science  41 upvotes 9 months ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.