learn Valproic acid
an anticonvulsant repurposed for hair loss via histone inhibition
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research Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures
EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
research Aqueous Extract of Asiasari Radix Inhibits Formalin-Induced Hyperalgesia via NMDA Receptors
Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.
research Mitochondrial Dysfunction in Diabetic Neuropathy May Be Involved in the Development of Neuropathic Pain via a Reduction in Neurosteroid Synthesis
Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.
research Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABA-A Receptors
Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
research Brain Allopregnanolone Induces Marked Scratching Behavior in Diet-Induced Atopic Dermatitis Mouse Model
A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.
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5 / 45 resultscommunity Kintor’s KX-826 Pyrilutamide!!
KX-826 hair loss treatment completed trials with mild side effects. GT20029 may be ultimate cure, destroying androgen receptors causing baldness.
community Horrible news, Stemson Therapeutics has shut down
Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.
community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)
Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.
community Do it yourself topical Fin and Min solution works
A homemade topical solution of finasteride and minoxidil effectively stopped hair shedding and promoted regrowth without side effects. Users shared experiences and discussed different concentrations and application methods.
community 36yo male, NW6, 2.5mth dut/minox
A 36-year-old male using dutasteride and minoxidil has seen significant hair regrowth, confirmed by a dermatologist and supported by before-and-after photos. He plans to increase his oral minoxidil dosage and add dermapen to his routine.