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GlossaryGefitinib

inhibits EGFR to treat certain non-small cell lung cancers

Gefitinib, also known as Iressa, is a medication used to treat certain types of non-small cell lung cancer. It works by inhibiting the epidermal growth factor receptor (EGFR), which is involved in the growth and spread of cancer cells. By blocking this receptor, gefitinib can help slow down or stop the progression of the cancer.

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research Nonscarring inflammatory alopecia associated with the epidermal growth factor receptor inhibitor gefitinib

57 citations , August 2006 in “Journal of the American Academy of Dermatology”

Gefitinib can cause hair loss without scarring.

research Gefitinib: an adverse effects profile

44 citations , April 2006 in “Expert opinion on drug safety”

Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.

research Erosive Pustular Dermatosis of the Scalp-Like Eruption due to Gefitinib: Case Report and Review of the Literature of Alopecia Associated with EGFR Inhibitors

36 citations , January 2012 in “Dermatology”

Stopping gefitinib improved scalp condition in a woman with lung cancer.

research Trichoscopic Findings of Erosive Pustular Dermatosis of the Scalp Associated with Gefitinib

21 citations , June 2017 in “Case Reports in Dermatology”

Reducing gefitinib dosage improved hair loss, but scarring remained.

research Gefitinib-induced hair alterations: Figure 1

7 citations , January 2009 in “BMJ Case Reports”

Gefitinib can cause slower, finer, brittle, and curly scalp hair.

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learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

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