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Role of Polymorphism of the Androgen Receptor Gene and Non-Random X Chromosome Inactivation in the Genesis of Androgenic Alopecia in Women of Childbearing Potential

research Role of polymorphism of the androgen receptor gene and non-random X chromosome inactivation in the genesis of androgenic alopecia in women of childbearing potential

April 2011 in “Vestnik dermatologii i venerologii”

Certain gene variations and irregular X chromosome activity may contribute to hair loss in women who can have children.

Role of Polymorphism of the Androgen Receptor Gene and Non-Random X Chromosome Inactivation in the Pathogenesis of Androgenic Alopecia

research Role of polymorphism of the androgen receptor gene andnon-random x chromosome inactivation in the pathogenesisof androgenic alopecia

December 2010 in “Vestnik dermatologii i venerologii”

Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.

research The role of the androgen receptor gene CAG repeat polymorphism and X-chromosome inactivation pattern in postmenopausal female pattern hair loss

2 citations , January 2008 in “Oxford University Research Archive (ORA) (University of Oxford)”

research Relationship of a Novel c.429delC Deletion in Hairless Gene HR with Alopecia in Two Families from Southern Punjab, Pakistan

August 2020 in “Pakistan Journal of Zoology”

A new mutation in the Hairless gene causes hair loss in two Pakistani families.

research Inactivation of autophagy leads to changes in sebaceous gland morphology and function

27 citations , July 2018 in “Experimental dermatology”

Autophagy is crucial for normal sebaceous gland function and sebum composition.

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community How far are we from gene editing stem cells and implanting them?

in Research/Science 14 upvotes 4 months ago

Gene editing for hair loss is not yet viable due to technological and economic challenges. Current treatments like Minoxidil, finasteride, and hair transplants remain the most practical options.

community Seeking Suggestions for VEGF Gene Therapy in Hair Transplants

in Basic Questions 75 upvotes 3 months ago

A user is exploring VEGF gene therapy to enhance hair transplant results, considering measuring hair shaft diameter and growth rate. Suggestions include using phototrichograms and possibly adding PRP, though its effectiveness is uncertain.

community Proof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. PP405 won’t work. AMP-303 might!

in Research/Science 145 upvotes 4 months ago

Hair loss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hair loss, unlike Pelage's PP405.

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