112 citations
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January 2004 in “The International journal of developmental biology” Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
March 2026 in “Experimental Dermatology” The new model helps understand and develop treatments for genetic skin disorders like AEC.
6 citations
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March 2024 in “Journal of Clinical Laboratory Analysis” Certain genetic variations in IGF2BP2 and IGFBP3 are linked to a higher risk of PCOS.
June 2026 in “Health Science Reports” The document presents a theoretical model for treating androgenetic alopecia (AGA) using the STEAP3 protein, based on recent genetic insights into the condition. Current treatments like minoxidil and 5α-reductase inhibitors have limitations and side effects. The study reviews genetic mutations in genes such as AR, EDA2R, HDAC9, PAX1, and FOXA2, which are involved in various molecular pathways. The proposed model suggests that STEAP3 could inactivate GSK3β, allowing β-catenin to enter the cell nucleus, potentially addressing the root cause of AGA. However, this model is purely theoretical and requires further laboratory and clinical validation.
23 citations
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July 2003 in “Pharmacology, Biochemistry and Behavior” Finasteride blocks progesterone's effect on absence seizures in rats.