14 citations
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September 1986 in “Archives of Dermatology”
Women with low SHBG levels and a high 3a-diol G to SHBG ratio are likely to experience female pattern baldness, possibly due to a slight excess of androgens affecting sensitivehairbulbs.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”
A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
Creatine may accelerate hair loss in those genetically predisposed, with some users reporting increased shedding while taking it and improvement after stopping. Some users use treatments like finasteride and minoxidil, while opinions on creatine's impact vary.
PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.
A 24-year-old male is considering a hair transplant after unsuccessful attempts with oral minoxidil, topical finasteride, ketoconazole shampoo, and lifestyle changes. He believes smoking and caffeine may worsen his hair loss and is looking into hair fibers for temporary coverage.
Creatine may increase DHT levels, potentially affecting hair loss in some individuals, but opinions vary. Some users report hair loss while on creatine, while others see no effect, especially when using treatments like finasteride, minoxidil, and microneedling.
Diet and lifestyle changes can reduce hair shedding but won't regrow hair lost to genetic male pattern baldness. Treatments like finasteride and dutasteride are necessary for significant hair regrowth.