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GlossaryGenetics

study of heredity and variation in living organisms

Genetics is the study of how traits and characteristics are passed down from parents to their offspring through genes. It involves understanding the structure, function, and behavior of genes, which are segments of DNA that carry the instructions for making proteins and other molecules essential for life. This field helps explain why individuals inherit certain physical features, susceptibilities to diseases, and other biological attributes.

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Research

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Large-Scale Genome-Wide Meta-Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria

research Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

308 citations , December 2018 in “PLOS Genetics”

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

research Genetic, hormonal and metabolic aspects of PCOS: an update

258 citations , July 2016 in “Reproductive Biology and Endocrinology”

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia

195 citations , June 2005 in “American Journal of Human Genetics”

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

research Genetics of polycystic ovary syndrome: searching for the way out of the labyrinth

179 citations , July 2005 in “Human Reproduction Update”

PCOS is influenced by both genes and environment, but its exact genetic cause is still unclear.

research Genetic Variation at the MC1R Locus and the Time since Loss of Human Body Hair

152 citations , January 2004 in “Current anthropology”

Humans lost body hair relatively recently in evolution.

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community Genetics are so weird and unpredictable

in Minoxidil 118 upvotes 1 year ago

The user experienced male pattern baldness starting at 18, tried finasteride with no success, and switched to dutasteride, which halted hair loss. Minoxidil had no effect for them, while their brother, who didn't use AR inhibitors, maintained a juvenile hairline and successfully grew a beard with minoxidil, highlighting the unpredictable nature of genetics in hair loss and treatment response.

community How a follicle next to it is so genetically different that it never miniaturized??

in Chat 219 upvotes 10 months ago

Genetic differences in hair follicles affect hair loss patterns. Treatments discussed include finasteride, dutasteride, minoxidil, and RU58841.

community Genetic variations associated with response to Dutasteride. Why is it never mentioned?

in Research/Science 26 upvotes 1 year ago

Genetic variations influence how people respond to dutasteride for hair loss, with some benefiting more from finasteride. Dutasteride is effective for most, but genetic differences may cause it to be less effective for some.

community Genetic testing to determine individualized hairloss treatment?

in Research/Science 10 upvotes 3 years ago

A user discusses a company, Roots by Genetic Arts, that offers a genetic test for hair loss to create personalized treatments, and is curious about its legitimacy and the science behind it. The company tests 16 genes related to hair loss and compounds a topical treatment based on the results.

community Losing the genetic lottery - venting

in Chat 67 upvotes 3 months ago

The user is experiencing hair loss and has tried various treatments including topical and oral finasteride, minoxidil, dutasteride, and ketoconazole, but continues to lose hair. They are considering alternative solutions like hair systems due to the lack of improvement and a scalp condition called CVG.

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