research SnapshotDx Quiz: August 2019
The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.
Search
forLearn
0 / 0 results — no results
Research
5 / 1000+ results 
research Insights into Male Androgenetic Alopecia: Differential Gene Expression Profiling of Plucked Hair Follicles and Integration with Genetic Data
Gene differences found in hair follicles linked to male baldness.
research Investigation of Four Novel Male Androgenetic Alopecia Susceptibility Loci: No Association with Female Pattern Hair Loss
No link found between new male baldness genes and female hair loss.
research The Biology and Genomics of Human Hair Follicles: A Focus on Androgenetic Alopecia
Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
research Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies
This review emphasizes the role of genetics in understanding and treating male pattern hair loss (MPHL), highlighting the identification of numerous genetic loci related to androgen signaling and WNT pathways. It suggests a shift towards genetically informed treatment strategies, using pharmacogenetic markers and polygenic scores to tailor therapies like minoxidil and 5α-reductase inhibitors. The study involved 26,607 participants and a pharmacogenetic cohort of 252 individuals, supporting the integration of genetics into therapeutic decision-making. While complete follicular restoration is unlikely, realistic outcomes include stabilization, modest regrowth, or delayed progression. Emerging therapies targeting genetic pathways and innovative approaches like RNA-based androgen receptor silencing are discussed as potential advancements. The review underscores the need for further validation and diverse cohort studies to establish clinical decision models.
Community Join
5 / 43 resultscommunity Hair loss research is a money grab
Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.
community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments
Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.
community Do you believe there will be a game changing treatment in the next 10 years?
Users discuss potential game-changing hair loss treatments in the next 10 years. Some mention KX-826, SCUBE3, and stem cells as promising options, while others express doubt due to past disappointments and lack of focused research.
community My Theory Regarding a Cause and Cure for Androgenetic Alopecia
Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.
community UPDATE: The theory that explains everything. Please help me make this big!
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.