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Combinatorial Expression of Cell Cycle Regulators Is More Suitable for Immortalization Than Oncogenic Methods in Dermal Papilla Cells

research Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells

5 citations , January 2021 in “iScience”

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

research Understanding skin morphogenesis across developmental, regenerative and evolutionary levels

2 citations , April 2019 in “Experimental Dermatology”

The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.

research scMC learns biological variation through the alignment of multiple single-cell genomics datasets

822 citations , January 2021 in “Genome biology”

scMC effectively separates biological signals from technical noise in single-cell genomics data.

research Genomic prediction and genome-wide association studies of morphological traits and distraction index in Korean Sapsaree dogs

2 citations , November 2024 in “PLoS ONE”

Genomic prediction can improve breeding strategies for Korean Sapsaree dogs.

research Challenges associated with the identification of germline variants on myeloid malignancy genomic profiling—a Singaporean experience

1 citations , October 2023 in “Frontiers in Oncology”

Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.

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community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 14 upvotes 6 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community Is it sufficient to block scalp DHT topically, or is it also necessary to reduce serum DHT? (My Question is Elaborated Below)

in Research/Science 17 upvotes 1 year ago

Topical finasteride can be as effective as oral finasteride for hair regrowth with fewer systemic side effects, but precise dosing is essential. Combining oral dutasteride with topical finasteride is not recommended due to dutasteride's stronger inhibition.

community if Post Finasteride Syndrome is real. Why is it only the negative effects and not positive have log term effect?

in Finasteride/Dutasteride 63 upvotes 3 months ago

Finasteride is used for hair loss, with mixed reports of no side effects and claims of long-term negative effects known as Post Finasteride Syndrome (PFS). The conversation debates the existence and causes of PFS, with differing opinions on whether it is psychological or real.

community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 4 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community Rhamnose-Mediated Modulation of Hair Follicle Growth: Insights from Chemical Genomics

in Research 47 upvotes 1 year ago

Rhamnose may promote hair growth and pigmentation, suggesting it as a potential hair loss treatment. The conversation discusses its potential alongside known treatments like Minoxidil, finasteride, and RU58841.

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