35 citations
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February 2023 in “Biomolecules” Granzyme B is important in autoimmune skin diseases and could be a new treatment target.
2 citations
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July 2019 in “Pakistan Journal of Biological Sciences” Perforin and granzyme-B may influence hormone levels in women with PCOS.
Granzyme B accelerates skin aging and impairs healing by breaking down important skin components.
127 citations
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January 2000 in “Journal of Investigative Dermatology” Cytotoxic T cells cause hair loss in chronic alopecia areata.
52 citations
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March 2010 in “British Journal of Dermatology” Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.