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research Laser capture microdissection as a method for investigating the human hair follicle microbiome reveals region-specific differences in the bacteriome profile

8 citations , March 2023 in “BMC Research Notes”

Laser-capture microdissection effectively analyzes hair follicle microbiomes, revealing region-specific bacterial differences.

research 551 Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.

research 731 Generation of a laser capture microdissection and RNAseq-based human anagen hair follicle transcriptome atlas

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scientists created a detailed map of gene activity in different parts of human hair follicles.

research Laser microdissection and DNA typing of cells from single hair follicles

45 citations , December 2004 in “Forensic Science International”

Laser microdissection helps get DNA from single hair follicles for better forensic analysis.

research Isolating Dermal Papilla Cells from Human Hair Follicles Using Microdissection and Enzyme Digestion

6 citations , January 2020 in “Methods in molecular biology”

The method successfully isolates cells that are important for hair growth and could help study hair loss.

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Community Join

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community Do hair follicles ever really "die"? Or does all your front, mid, and crown hair just become vellus?

in Chat 141 upvotes 1 year ago

Hair follicles don't truly die but become severely miniaturized. Treatments like finasteride, dutasteride, and minoxidil can help restore hair by providing nutrients and reducing harmful effects on hair roots.

community Reminder: NURTURE those dormant hair follicles for as long as you can until PP405 comes out in 2028-2030

in Treatment 191 upvotes 8 months ago

PP405 is anticipated as a future treatment for dormant hair follicles, but its effectiveness and safety are uncertain. Current treatments include oral minoxidil and microneedling, with some avoiding finasteride due to side effects.

community 6 month update fin, min, micro-needle

in Progress Pictures 436 upvotes 1 year ago

The user experienced significant hair regrowth and improved hair quality after six months of using oral minoxidil, finasteride, and micro-needling. They reported increased libido initially but no other side effects, and they plan to continue the treatment.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 2 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community HairClone developing cell replacement treatments for Hair Loss

7 upvotes 7 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

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Clinics

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learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth