October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”
A protein called EGFR protects hairfollicle stem cells, and when it's disrupted, hairfollicles can be damaged, but blocking certain pathways can restore hair growth.
Verteporfin reduces scar tissue in hair transplants but doesn't significantly regrow hairfollicles. More testing is needed to determine its effectiveness.
User discusses verteporfin for hair regrowth through "super microneedling" and preventing scarring. They mention a case of an old man regrowing hair after a head injury and suggest verteporfin could recreate this result.
Topical Metformin shows potential for regenerating hairfollicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.
Exploring the potential of using verteporfin during hair transplants to minimize scarring and regenerate follicles, as well as discussing a possible standardized protocol for this treatment.
A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hairfollicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.