Exosome hair therapy involves injecting stemcell-derived exosomes into the scalp to boost hairfollicle regeneration and repair. Exosomes, which are not stemcells but products of them, contain bioactive chemicals and specific growth factors that promote new blood vessel formation, increase cell proliferation, reduce inflammation, and improve tissue repair, all crucial for hair health.
Stemcellhair transplants use stemcells from fat tissue to reactivate inactive hairfollicles, but results are inconsistent and not widely shared. Traditional treatments like finasteride and minoxidil often show better results.
Adipose-derivedstemcell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.
Mallia Aesthetics has developed MAL-838, a hormone-free product derived from sCD83, which stimulates hair growth without disrupting the skin microbiome. sCD83 promotes hair growth by activating hairfollicles and preventing cell death, offering a localized treatment without systemic side effects.
A breakthrough in hairfollicle cultivation using induced pluripotent stemcells (iPSCs) has been achieved, producing large hairfollicles suitable for transplantation. Clinical trials for this hair multiplication technology are planned in partnership with Yinguan Biotechnology.