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GlossaryMelanogenesis

process of producing melanin in skin and hair cells

Melanogenesis is the process by which the skin and hair produce melanin, the pigment responsible for their color. This process occurs in specialized cells called melanocytes and involves a series of biochemical reactions, primarily catalyzed by the enzyme tyrosinase. Melanogenesis is influenced by genetic factors, UV exposure, and hormonal changes, and plays a crucial role in protecting the skin from UV radiation.

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Research

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research ABSENCE OF H2O2 BREAKDOWN IN HUMAN HAIR MEDULLA IMPLICATIONS IN FOLLICULAR MELANOGENESIS

1 citations , September 2018 in “International journal of research - granthaalayah”

Human hair medulla doesn't break down hydrogen peroxide, which may affect hair color formation.

research Influence of prostaglandin F_2α and its analogues on hair regrowth and follicular melanogenesis in a murine model

103 citations , April 2005 in “Experimental dermatology”

Prostaglandin F2alpha and related compounds can increase hair growth and darken hair in mice.

research Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis

29 citations , January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

research Involvement of the central hypothalamic-pituitary-adrenal axis in hair growth and melanogenesis among different mouse strains

6 citations , October 2018 in “PLoS ONE”

Stress can slow hair growth and affect skin color by impacting the body's stress response system.

research Hair Follicle Melanogenesis Reflected in Hair Pigmentation as a Developmental Factor in Alopecia Areata

3 citations , January 2021 in “Skin appendage disorders”

Hair color is not a risk factor for developing alopecia areata.

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community Making your own RT1640 in China

in Research/Science 4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community Hair Color Change and Shedding: Telogen Effluvium or AGA?

in Basic Questions 36 upvotes 1 week ago

The conversation discusses hair color change and shedding, questioning if it's due to Telogen Effluvium or Androgenetic Alopecia (AGA). Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Hair growth journey -7th Month Progress from Lahore Pakistan

in Journals / Progress Pictures 47 upvotes 2 weeks ago

A 45-year-old from Lahore, Pakistan, shares their 7-month hair growth progress after starting a new hair regeneration treatment. Previous treatments with minoxidil and finasteride showed no progress.

community Thinning Hair After 1200 Graft Transplant and Minoxidil/Finasteride Use

in Hair Transplants 96 upvotes 3 weeks ago

After a 1,200 graft hair transplant and using minoxidil and finasteride, the user's hair initially improved but later thinned and changed texture. They are seeking advice on this issue and have a dermatologist appointment scheduled.

community Hair regrowth without drugs (99% natural) 25M

in Progress Pictures 423 upvotes 2 months ago

A user shared their experience with hair regrowth using supplements like NAC and DIM, and briefly using minoxidil with microneedling. They reported some improvement in hair density, but the community questioned the effectiveness compared to traditional treatments like finasteride.

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