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research Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis

23 citations , October 2021 in “Cell Stem Cell”

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

research Pathologic Diagnosis of Central Centrifugal Cicatricial Alopecia on Horizontal Sections

29 citations , September 2014 in “American Journal of Dermatopathology”

Horizontal sections of scalp biopsies are good for diagnosing Central Centrifugal Cicatricial Alopecia and help customize treatment.

Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression

research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression

128 citations , March 2006 in “American Journal of Pathology”

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

research Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling

65 citations , September 2004 in “The American journal of pathology”

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.

research 5α-Reductase: History and Clinical Importance

20 citations , January 2004 in “PubMed Central”

5α-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT levels.

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community Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.

in Research/Science 48 upvotes 6 months ago

Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.

community Yo!! One year update chooms!!!!

in Progress Pictures 2858 upvotes 1 year ago

Significant hair regrowth was achieved using 0.5mg oral finasteride, a topical mix of finasteride and minoxidil, and dermastamping. Initial side effects like achy testicles were managed by adjusting the regimen.

community how do you produce more thick white cum while on fin?

in Finasteride/Dutasteride 139 upvotes 4 months ago

Finasteride can reduce semen volume due to prostate shrinkage but doesn't affect fertility. To increase semen volume, consider zinc, lecithin, and reducing finasteride dosage.

community Occipitalis Muscle Tension Theory

in Treatment 14 upvotes 6 months ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

community Anybody else obsessively searching for pp405 and counting the days?

in Technology 70 upvotes 1 year ago

People are eagerly awaiting the release of PP405, a new hair loss treatment. Some are using minoxidil and finasteride in the meantime, but there are concerns about scams and unverified products.

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