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research Trichoscopy in Hair Shaft Disorders

36 citations , August 2018 in “Dermatologic Clinics”

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

research Hair Shaft Dysplasias

19 citations , March 1988 in “International Journal of Dermatology”

Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.

research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature

15 citations , June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Secretory Phospholipase A2-IIA Overexpressing Mice Exhibit Cyclic Alopecia Mediated Through Aberrant Hair Shaft Differentiation and Impaired Wound Healing Response

research Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response

7 citations , September 2017 in “Scientific Reports”

Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.

Mitochondrial DNA Variation in Human Hair Shafts Influenced by Physical Characteristics: A Massively Parallel Sequencing Analysis

research Mitochondrial DNA Variation in Human Hair Shafts Influenced by Physical Characteristics: A Massively Parallel Sequencing Analysis

July 2026 in “Genes”

Hair shaft characteristics can affect mitochondrial DNA metrics, but more research is needed.

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community Microneedling must reach the stem cells in the upper hair shaft

in Treatment 80 upvotes 4 years ago

Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.

community After using finasteride, did you notice an improvement in the hair shaft in terms of looking more “alive” and shiny?

in Finasteride/Dutasteride 2 upvotes 6 months ago

Finasteride users reported improvements in hair appearance, including increased thickness, shine, and darker color. Some users noticed their hair looked healthier and less sunburned after starting the treatment.

community Seeking Suggestions for VEGF Gene Therapy in Hair Transplants

in Basic Questions 75 upvotes 4 months ago

A user is exploring VEGF gene therapy to enhance hair transplant results, considering measuring hair shaft diameter and growth rate. Suggestions include using phototrichograms and possibly adding PRP, though its effectiveness is uncertain.

community Oral Minoxidil Study of 60 AGA patients

in Minoxidil 70 upvotes 4 years ago

Oral minoxidil treatment increased hair density and shaft caliber in AGA patients. Side effects included hypertrichosis and lower extremity edema, with younger patients experiencing fewer side effects.

community Bro I didn’t even hit 25 and my scalp already applied for early retirement 💀

in Product 158 upvotes 11 months ago

Young men experiencing early hair loss and discussing treatments like Minoxidil, finasteride, and RU58841. Many share feelings of frustration and coping strategies, with some finding solace in treatments and mindset shifts.

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