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GlossaryHaloperidol

antipsychotic medication used to treat schizophrenia and acute psychosis

Haloperidol, also known by the brand name Haldol, is an antipsychotic medication primarily used to treat schizophrenia and acute psychotic states. It works by blocking dopamine receptors in the brain, which helps to reduce symptoms such as hallucinations, delusions, and agitation.

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learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

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Research

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research The measurement of haloperidol and reduced haloperidol in hair as an index of dosage history.

72 citations , February 1990 in “British Journal of Clinical Pharmacology”

Hair analysis can track haloperidol dosage history.

research Alopecia areata associated with haloperidol decanoate long-acting injection

2 citations , January 2012 in “Australian and New Zealand journal of psychiatry”

Haloperidol decanoate can cause alopecia areata.

research Response of Hemiballismus to Haloperidol-Reply

1 citations , February 1976 in “JAMA”

Haloperidol effectively treated hemiballismus, but spontaneous improvement wasn't ruled out; rapid weight loss can cause hair loss with good regrowth chances.

research Serum prolactin and dehydroepiandrosterone concentrations during the summer and winter hair growth cycles of mink (Mustela vison)

18 citations , November 1998 in “Comparative biochemistry and physiology. Part A, Molecular & integrative physiology”

Changes in prolactin and DHEA levels are not required for the start of mink hair growth cycles.

research Follicular mycosis fungoides associated with lithium

17 citations , February 2001 in “Journal of the American Academy of Dermatology”

Lithium can cause skin changes similar to mycosis fungoides.

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Community Join

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community Horrible news, Stemson Therapeutics has shut down

in Technology 195 upvotes 1 year ago

Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

in Chat 13 upvotes 4 months ago

Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

community Has the user in the HMI-115 trial shared his photos now since it's April?

in Update 25 upvotes 3 years ago

A user who was part of an ongoing trial for a prolactin blocker and had regrowth, but the progress photos were not shared due to negative reactions from other users. Treatments mentioned include HMI-115, Minoxidil, Finasteride, and RU58841.

community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 39 upvotes 3 years ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

community Estradiol mesotherapy / idea feedback

in Female 7 upvotes 1 year ago

The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

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