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research Genome-wide shifts in gene expression induced in theca-interstitial cells by inflammatory stimuli

September 2018 in “Fertility and Sterility”

African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.

research Isosexual Precocious Pseudopuberty Secondary to a Testosterone-Secreting Leydig Cell Testicular Tumour: True Isosexual Development Early After Surgery*

17 citations , April 2009 in “Andrologia”

A boy's early puberty caused by a testicular tumor returned to normal after surgery.

Pharmacological Control of Reproduction in Dogs and Cats

research Pharmacological Control of Reproduction in the Dog and Cat

January 2019

Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.

research Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility

39 citations , January 2019 in “The World Journal of Men's Health”

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Dihydrotestosterone Stimulates 5α-Reductase Activity in Pubic Skin Fibroblasts

research Dihydrotestosterone Stimulates 5a-Reductase Activity in Pubic Skin Fibroblasts*

57 citations , February 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

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Community Join

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community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 4 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community Used finasteride 10 years ago and I still suffer from severe ED. I have blood test results attached

in Finasteride 9 upvotes 7 years ago

A user took finasteride for hair loss 10 years ago, stopped after a month, and has since suffered from severe erectile dysfunction (ED) and other symptoms. They shared blood test results seeking advice for their condition, and others discussed similar experiences with finasteride and related drugs.

community A little more than a month using red light therapy. I'm surprised by the progress.

in Is this regrowth? 258 upvotes 3 months ago

Red light therapy has shown promising results in hair regrowth for the user, who avoids minoxidil and finasteride due to side effects. The user follows a healthy lifestyle with diet, exercise, and sauna use, and will continue monitoring the therapy's effectiveness.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 443 upvotes 6 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 5 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

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