research Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle 51 citations , September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
research KLHL24-Mediated Hair Follicle Stem Cells Structural Disruption Causes Alopecia 4 citations , January 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.
research H2AK119ub dynamics control hair follicle stem cell quiescence 2 citations , December 2025 in “Nature Communications” H2AK119ub helps keep hair follicle stem cells in a resting state, preventing early aging.
research ADAM17 variant causes hair loss via ubiquitin ligase TRIM47 mediated degradation May 2024 in “JCI insight” A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.
research A family business: stem cell progeny join the niche to regulate homeostasis 254 citations , January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss