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GlossaryStratum Corneum (Horny Layer)

outermost skin layer composed of dead, keratinized cells

The Stratum Corneum, also known as the Horny Layer, is the outermost layer of the epidermis, consisting of dead, flattened skin cells that are rich in keratin. This layer acts as a primary barrier to protect underlying tissues from infection, dehydration, and mechanical stress, playing a crucial role in maintaining skin hydration and overall health.

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research A Histochemical Examination of the Epidermis of the Southern Elephant Seal (Mirounga Leonina L.) During the Telogen Stage of Hair Growth

8 citations , February 1968 in “Australian Journal of Zoology”

The southern elephant seal's skin layer helps waterproof the skin by being tightly connected to hair shafts.

research Bikunin, a Serine Protease Inhibitor, Is Present on the Cell Boundary of Epidermis

13 citations , August 1999 in “Journal of Investigative Dermatology”

Bikunin is found on the cell boundaries of certain skin layers and may help regulate skin and hair functions.

research Epidermal Structure Created by Canine Hair Follicle Keratinocytes Enriched with Bulge Cells in a Three-Dimensional Skin Equivalent Model In Vitro: Implications for Regenerative Therapy of Canine Epidermis

11 citations , January 2013 in “Veterinary dermatology”

Keratinocytes from dog hair follicles can create a functional skin layer in a lab model, useful for dog skin therapy.

research Ultrastructure of the Contrasting Types of Keratinization Seen in the Tail Epidermis of the Laboratory Mouse Mus Musculus

11 citations , January 1977 in “Archives of dermatological research”

Mouse tail skin has different keratinization near hair follicles and scales.

research Keratoma Hereditaria Mutilans (Vohwinkel's Disease) with Congenital Alopecia Universalis (Atrichia Congenita)

14 citations , June 1989 in “Journal of dermatology”

Three siblings had both Vohwinkel's disease and congenital alopecia, with no effective treatment.

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community Balding at the age of 17 years old

in Chat 8 upvotes 1 year ago

A 17-year-old experiencing hair loss is using Minoxidil but is hesitant about Finasteride due to potential side effects. Others recommend Finasteride for its effectiveness and suggest alternatives like vitamins and derma rollers.

community so pissed off at the world. hairloss is a nightmare in your early 20's (WARNING, RANT)

in Treatment 153 upvotes 4 years ago

User frustrated with lack of results from finasteride and minoxidil for hair loss. Others suggest checking for other health issues, focusing on fitness, and considering alternative treatments.

community Quit finasteride after 15+ years

in Update 970 upvotes 5 months ago

A user stopped finasteride after 15 years due to severe side effects, which improved after quitting. They maintained most of their hair and are considering alternatives like topical treatments or RU58841.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 117 upvotes 1 year ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community 1.25mg of Fin and 5% topical minoxidil once a day. 8 months progress. Diffuse thinning

in Progress Pictures 458 upvotes 3 years ago

This user experienced improvements in their hair density and texture through the use of finasteride (1.25mg) and minoxidil (5%) applied topically once a day over 8 months, with no reported side effects other than slightly lowered libido.

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