research Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol
Human hair follicles can produce cortisol like the body's stress response system.
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5 / 663 resultsresearch Maternal Influence on Child HPA Axis: A Prospective Study of Cortisol Levels in Hair
Maternal stress during pregnancy affects a child's stress levels.
research HPA axis stress reactivity and hair cortisol concentrations in recently detoxified alcoholics and healthy controls with and without childhood maltreatment
Alcohol dependence affects stress hormone levels more than childhood maltreatment.
research The human hair follicle has established a fully functional peripheral equivalent of the hypothamalic‐pituitary‐adrenal‐axis (HPA)
Human hair follicles can produce stress hormones like the body's main stress response system.
research Localized alopecia and suppression of hypothalamic-pituitary-adrenal (HPA) axis in dogs following treatment with difluprednate 0.05% ophthalmic emulsion (Durezol®)
Long-term use of difluprednate eye drops in dogs can lead to hair loss and hormone imbalance.
Community Join
5 / 43 resultscommunity CB-03-01 / Breezula Personal Results
The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.
community EMA is re-examining Winlevi (clascoterone at lower concentration)
Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.
community There’s actually a quite good chance that next year, we might see a new treatment get FDA approval for the first time in nearly three decades.
Breezula, a potential new hair loss treatment, may receive FDA approval soon, but it is expected to be a weaker alternative to finasteride and minoxidil. Concerns include its twice-daily application and possible side effects like HPA axis suppression.
community KX826 is better than RU58841. A legitimate option for those who cant use fin or dut.
KX826 is considered a legitimate option for those who cannot use finasteride or dutasteride, but many users report it as ineffective compared to RU58841. RU58841 is favored by some due to anecdotal evidence of effectiveness, despite the lack of published clinical data.
community Is hydrocortisone that bad for your scalp?
Hydrocortisone is not recommended for long-term use on the scalp due to potential side effects like thinning and steroid-related issues. Alternatives like foam minoxidil or oral minoxidil are suggested, though foam may be less effective.
Clinics
6 / 45 results- 24
Hair Loss TreatmentsAxis Stem Cell InstituteKirkland, WA · US - 73Hair TransplantDR AWISH SKIN HAIR LASER COSMETIC CLINICJaipur, Rajasthan · IN
- 22Hair TransplantHair Loss TreatmentsDermatologyDr Aishwarya PatilPimpri-Chinchwad, Maharashtra · IN
- 32SMPCHRISTINE ALISON PERMANENT MAKE-UP, LASER & SKIN CLINIC LTDEdinburgh · GB
- 18
TrichologyHair TransplantDr Alisson Fonseca Transplante CapilarMontes Claros, MG · BR - 31Hair TransplantKlinik Amisi BangiBandar Baru Bangi, Selangor · MY
Experts
6 / 32 results- 88
Hair Transplant SurgeonDr. Cesar Aristeiguieta, MD, FACEP
Houston, TX, United States
- 51
TrichologistDean Alister
Johannesburg, South Africa
- 38
Hair Transplant SurgeonDr. Ivana Asis, MD
Mendoza, MZ, Argentina
- 19Hair Transplant Surgeon
Dr. Katerina Alisavaki, MD
London, United Kingdom
- 23
Hair Transplant SurgeonDr. Katerina Alisavaki, MD
Cape Town, South Africa
- 12
SMP SpecialistPaola Aispuro
Stockton, CA, United States
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