research HPA axis stress reactivity and hair cortisol concentrations in recently detoxified alcoholics and healthy controls with and without childhood maltreatment
Alcohol dependence affects stress hormone levels more than childhood maltreatment.
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research HPA Axis Variation and ACEs; Childhood Sexual Trauma is Associated with Lower Hair Cortisol in Adulthood
Childhood sexual trauma, especially between ages 5-7, is linked to lower cortisol levels in adult hair, suggesting long-term stress response changes.
research Does hair cortisol concentration reflect measurable regulatory biology of the HPA axis in healthy humans?
Hair cortisol concentration partly reflects HPA axis regulation but doesn't capture all its complexities.
research The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli
Finasteride reduces response to stress and rewards, affecting behavior and mental health.
research Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones
Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
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4 / 1000+ resultscommunity How to reduce cortisol (stress hormone) naturally?
The conversation discusses natural ways to reduce cortisol, such as avoiding caffeine, getting proper sleep, syncing with the sun, walking in nature, breathing exercises, increasing calories, and not doing keto. Magnesium supplements are recommended for stress reduction.
community CB-03-01 / Breezula Personal Results
The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.
community EMA is re-examining Winlevi (clascoterone at lower concentration)
Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.
community There’s actually a quite good chance that next year, we might see a new treatment get FDA approval for the first time in nearly three decades.
Breezula, a potential new hair loss treatment, may receive FDA approval soon, but it is expected to be a weaker alternative to finasteride and minoxidil. Concerns include its twice-daily application and possible side effects like HPA axis suppression.
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Hair Loss TreatmentsAxis Stem Cell InstituteKirkland, WA · US - 57
Hair TransplantAHIS Aesthetics - The Hair Transplant Specialist in HSR Layout, BangaloreBengaluru, Karnataka · IN - 20Hair SystemsHair Loss TreatmentsAxioFukuoka · JP
- 26Hair Loss TreatmentsAxios Health and WellnessLongmont, CO · US
- 43Hair TransplantAHISMysuru, Karnataka · IN
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