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research Restoration of hair-inductive activity of cultured human follicular keratinocytes by co-culturing with dermal papilla cells

14 citations , September 2018 in “Biochemical and Biophysical Research Communications”

Growing hair cells with dermal cells can potentially treat hair loss.

Conditioned Media Obtained from Human Outer Root Sheath Follicular Keratinocyte Culture Activates Signalling Pathways That Contribute to Maintenance of Hair-Inducing Capacity and Increases Trichogenicity of Cultured Dermal Cells

research Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells

6 citations , July 2012 in “Experimental Dermatology”

The substance from human hair root cells can help maintain hair growth and make skin cells more capable of growing hair.

Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Promote Hair Regrowth in Alopecia Areata

research Exosomes derived from uMSCs promote hair regrowth in alopecia areata through accelerating human hair follicular keratinocyte proliferation and migration

November 2023 in “Cell Biology International”

Tiny particles from umbilical cord stem cells may help hair grow back in a type of hair loss.

research Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes

5 citations , October 2020 in “Frontiers in Cell and Developmental Biology”

Reducing FOXA2 in skin cells lowers their ability to grow hair.

research Regulation of PDGF and PDGF receptor in cultured dermal papilla cells and follicular keratinocytes of the human hair follicle

55 citations , September 2003 in “Experimental Dermatology”

PDGF signaling may play a role in hair growth cycle regulation.

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community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

in Research/Science 4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Minoxidil Response Bottlenecks: Why Sulfation and Transport Matter (And Where Tretinoin Fits In)

in Research 461 upvotes 1 year ago

Minoxidil's effectiveness is limited by the need for sulfation and proper transport to hair follicles, with tretinoin potentially enhancing its effects by promoting enzyme activity and keratinocyte differentiation. Tretinoin may improve minoxidil's response by boosting the expression of necessary enzymes and transporters.

community Short Peptides for Hair Loss: anyone tried any of these?

in Research/Science 12 upvotes 3 months ago

Various peptides are discussed for treating male pattern baldness, with some available for topical use like GHK-Cu and Ac-KGHK, while others remain in research stages. Users are interested in experiences and sourcing these treatments.