research Studies on basal cell carcinoma with emphasis on the role of the human homologue of the Drosophila patched gene November 1997 in “Open Archive (Karolinska Institutet)” PTCH gene mutations contribute to basal cell carcinoma development.
research Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1 380 citations , March 2000 in “Proceedings of the National Academy of Sciences” Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.
research The Genetics of Human Skin Disease 24 citations , October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Patched-assoziierte Tumoren: Modifikatorgene und Pathogenese February 2022 The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research Gene Expression in Rat Dermal Papilla Cells: Analysis of 2529 ESTs 14 citations , October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.