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Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function

17 citations , February 2015 in “Cell Death and Disease”

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

research Acute sensitivity of the oral mucosa to oncogenic K‐ras

12 citations , March 2011 in “Journal of pathology”

Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.

research Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations

41 citations , December 2011 in “The journal of investigative dermatology/Journal of investigative dermatology”

Deleting MED1 in skin cells causes hair loss and skin changes.

research KERATINS AND SKIN DISORDERS

28 citations , April 1996 in “Cell biology international”

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

research Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins

63 citations , July 2006 in “British Journal of Dermatology”

Psoriasis causes changes in certain keratins and shrinks sebaceous glands in the scalp.

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community So does oral minoxidil age your skin or not

in Minoxidil 46 upvotes 2 years ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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