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Netherton's syndrome may have a familial link and doesn't always include atopy.

Ichthyosis serpentina may be a variant linked to bamboo hair, with a possible genetic component.

Trichoscopy helps tell apart scalp lesions in pemphigus vulgaris and pemphigus foliaceus and is useful for choosing biopsy locations.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.