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GlossaryInterleukin-36 (IL36)

group of cytokines involved in immune system signaling and inflammation

Interleukin-36 (IL-36) is a group of cytokines, which are small proteins important for cell signaling in the immune system. These cytokines play a crucial role in inflammatory responses and are involved in the pathogenesis of various autoimmune and inflammatory diseases, such as psoriasis. IL-36 includes three agonists (IL-36α, IL-36β, and IL-36γ) and an antagonist (IL-36Ra), which together help regulate the body's immune response.

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research Real-World Single-Center Experience With 10 Cases of Generalized Pustular Psoriasis Successfully Treated With Ixekizumab

21 citations , September 2019 in “Journal of the American Academy of Dermatology”

Ixekizumab effectively treats generalized pustular psoriasis.

research Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review

1 citations , June 2023 in “Genes”

Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.

research Modulating Embryonic Signaling Pathways Paves the Way for Regeneration in Wound Healing

February 2024 in “Frontiers in physiology”

Modifying certain signals in the body can help wounds heal without scars and regrow hair.

Dimethyl Fumarate Ameliorates Delayed Wound Healing Due to IL-36Ra Deficiency Through Inhibition of NET Formation and Oxidative Stress

research Dimethyl Fumarate Ameliorates Delayed Wound Healing Due to IL-36Ra Deficiency Through Inhibition of NET Formation and Oxidative Stress

April 2023 in “Journal of Investigative Dermatology”

Dimethyl fumarate speeds up wound healing in IL-36Ra deficient mice by reducing NET formation and oxidative stress.

Identification of Potential Key Genes and Pathways Associated with the Pashmina Fiber Initiation Using RNA-Seq and Integrated Bioinformatics Analysis

research Identification of Potential Key Genes and Pathways Associated with the Pashmina Fiber Initiation Using RNA-Seq and Integrated Bioinformatics Analysis

36 citations , January 2021 in “Scientific Reports”

Key genes and pathways, including Wnt, NF-Kappa, and JAK-STAT, are crucial for starting Pashmina fiber growth in goats.

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