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Research

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research 0413 IL-17 Inhibitors vs. methotrexate in preventing new-onset psoriatic arthritis in psoriasis patients: a retrospective population-level analysis

July 2025 in “Journal of Investigative Dermatology”

IL-17 inhibitors are more effective than methotrexate in preventing psoriatic arthritis in psoriasis patients.

research 0248 Risk of infections in patients with hidradenitis suppurativa treated with TNF-α inhibitors vs. IL-17 inhibitors: A large-scale cohort study

July 2025 in “Journal of Investigative Dermatology”

research Alopecia Diffusa while Using Interleukin-17 Inhibitors against Psoriasis Vulgaris

20 citations , March 2019 in “Case Reports in Dermatology”

IL-17 inhibitors for psoriasis may cause unexpected hair loss.

research Netherton syndrome subtypes share IL-17/IL-36 signature with distinct IFN-α and allergic responses

59 citations , September 2021 in “Journal of Allergy and Clinical Immunology”

Netherton syndrome has two subtypes with shared immune traits but different allergic and immune responses, suggesting targeted treatments.

research Evaluation of the level of serum Interleukins (IL-2, IL-4, IL-15 andIL-17) and its relationship with disease severity in patients with alopecia areata

14 citations , July 2021 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

Interleukin levels are higher in alopecia areata patients but don't predict disease severity or duration.

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Community Join

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community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 6 months ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

community 3 months update on 3mg Dutasteride

in Chat 98 upvotes 4 months ago

The user saw no significant changes in hair loss after three months on 3mg Dutasteride, having previously used Finasteride and 0.5mg Dutasteride. They plan to continue the high dose for a year despite concerns about side effects and diminishing returns.

community 8 years of hair loss, turning 30 next month

in Progress Pictures 151 upvotes 1 year ago

The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.

community Topical T3 study - 1000% Growth. Anyone tried it?

in Research/Science 101 upvotes 4 years ago

The conversation discusses using T3 (triiodothyronine) as a topical treatment for hair growth, with some users noting it showed promising results in studies but lacked follow-up. Users express interest in trying T3 due to its potential effectiveness compared to Minoxidil.

community 12 mo update: oral (dut, min), topical (RU, min), microneedling

in Progress Pictures 348 upvotes 3 years ago

A user's 12 month update on treatment for hair loss, which include oral dutasteride and minoxidil, topical RU88541 and minoxidil, microneedling with hyaluronic acid and FinDuta, experiencing no side effects, positive results and inspiring other users.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn myristoyl pentapeptide-17

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

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Experts

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71
Hair Loss Specialist
Will Quaye
Crawley, United Kingdom

Clinics

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Will Quaye