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GlossaryImmune-Mediated

immune system mistakenly attacks the body's own cells

Immune-mediated refers to conditions or diseases that are caused by abnormal activity of the immune system, where it mistakenly attacks the body's own cells and tissues. This can lead to various health issues, such as inflammation, tissue damage, and organ dysfunction. Examples include autoimmune diseases like rheumatoid arthritis and alopecia areata, where the immune system targets hair follicles, leading to hair loss.

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Iron Deficiency in Immune-Mediated Inflammatory Skin Diseases: A Missing Link Between Systemic Inflammation, Immunometabolism, and Disease Burden

research Iron Deficiency in Immune-Mediated Inflammatory Skin Diseases: A Missing Link Between Systemic Inflammation, Immunometabolism, and Disease Burden

March 2026 in “Cells”

Iron deficiency worsens inflammatory skin diseases by disrupting iron balance and increasing inflammation.

research African Trypanosoma infection in a dog in France

11 citations , May 2011 in “Veterinary Record”

A dog in France died from an African parasite infection after traveling from Senegal.

research Systemic lupus erythematosus in a filly.

23 citations , December 1990 in “PubMed”

SLE should be considered in horses with immune-related skin issues.

research Bilaterally Symmetrical Alopecia With Reticulated Hyperpigmentation

5 citations , October 2012 in “Veterinary Pathology”

A Doberman Pinscher had a rare form of autoimmune disease causing hair loss and other severe symptoms.

research Celiac Disease: Beyond Diet and Food Awareness

January 2025 in “Foods”

Celiac disease requires more than just a gluten-free diet for effective management.

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

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Learn

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learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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