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research Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche

220 citations , June 2013 in “The Journal of Pathology”

Lichen planopilaris may be an autoimmune disease causing hair loss due to immune system issues in hair follicles.

research Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege

139 citations , October 2005 in “Journal of Investigative Dermatology”

The nail matrix has a reduced immune response, protecting it from autoimmunity.

research Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management

102 citations , December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse

research Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse

36 citations , April 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

research Immune privilege and alopecia areata

4 citations , April 2010 in “Expert review of dermatology”

Restoring immune privilege in hair follicles could help treat certain types of hair loss.

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Community Join

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community My Theory Of Androgenic Alopecia

in Research/Science 17 upvotes 8 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Duoxidil, Dutasteride and oral Minoxidil

in Minoxidil 89 upvotes 10 months ago

The conversation discusses hair regrowth treatments, specifically using a combination of oral and topical minoxidil, oral and topical dutasteride, and PRP. There is skepticism about the authenticity of the results, with some users questioning the changes in hair and skin appearance.

community Holding out for a miracle drug

in Is this regrowth? 59 upvotes 2 months ago

A 41-year-old male has been using a combination of treatments for hair regrowth, including finasteride, minoxidil, a laser cap, ketoconazole shampoo, and rosemary oil, with some progress noted. He is maintaining his current regimen in hopes of a future miracle drug while considering hair transplants and other treatments like dutasteride and copper peptides.

community I bought a microscope, how does my scalp/hairs look? I've been suffering diffuse thinning and hair loss after covid and never recovered (2 yrs ago) I eat healthy, in shape and workout.

in Progress Pictures 87 upvotes 2 years ago

A person with hair loss since COVID-19 is considering treatments like finasteride and minoxidil but is hesitant due to potential side effects. Suggestions include visiting a dermatologist, using a ketoconazole shampoo, and considering that post-COVID hair loss might be an autoimmune response.

community 5 years post hair transplant, 3 months on minoxidil only

in Minoxidil 322 upvotes 7 months ago

The user had a hair transplant five years ago and started using minoxidil three months ago. Commenters recommend adding finasteride or other DHT blockers to prevent further hair loss and maintain results.

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