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Research
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research In-Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device
The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.
research Evaluation of Personalized Skincare Through in-silico Gene Interactive Networks and Cellular Responses to UVR and Oxidative Stress
The study evaluated personalized skincare by analyzing single nucleotide polymorphisms (SNPs) in genes associated with skin types of European, Asian, and African origins. Using in-silico modeling and cultured dermal fibroblasts, researchers assessed cellular responses to ultraviolet radiation and oxidative stress. They found that SNPs in pigmentation-related genes influenced skin responses to photodamage, such as oxidative stress and inflammation. The study demonstrated that bioactive compounds like Resveratrol and Quercetin could modulate these responses. The findings suggested that understanding SNP-affected gene networks could aid in creating personalized skincare products tailored to different ethnic backgrounds.
research In silico structural prediction of human steroid 5α-reductase type II
Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.
research IN-SILICO STUDY OF BIOACTIVE COMPOUNDS OF NATURAL MATERIALS AS A JAK- SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION INHIBITOR FOR ANTI-ALOPECIA
Three compounds from Dadap leaves may help treat hair loss.
research Identification of Beta-Sitosterol and Stigmasterol as Possible Inhibitors of 5 Alpha-Reductase 1: An In-Silico Study
Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.
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5 / 1000+ resultscommunity Silicon Valley backed company aims to cure hair loss
A Silicon Valley-backed company aims to cure hair loss. Exciting advancements include mRNA therapies, gene editing, hair cloning, AR degraders, anti-androgens, cell-based rejuvenation, and AI-based drug discovery, with hopes for FDA approval of GT20029 within 10 years.
community Daily scalp massages lead to more hair loss or not?
The user applies castor oil and uses silicon scalp massagers daily, questioning if the massages cause more hair loss or if the hairs would fall out naturally. They believe the hairs are in the telogen phase and would shed regardless of the massage.
community VT Reedle Shot for hair growth?
The VT Reedle Shot, a skincare product using silica spicules, is discussed as a potential at-home alternative to microneedling for hair regrowth. It is suggested that different intensities may aid in hairline regrowth.
community 14 Months Dut/Minox/Microneedling + 13 Months HRT
The user shared their hair regrowth journey using treatments like dutasteride, minoxidil, microneedling, tretinoin, Nizoral, silica, biotin, and hormone replacement therapy (HRT) with cyproterone and estradiol. They reported substantial hairline improvement and some crown thinning, with hopes for further progress.
community Explanation for "dutasteride destroyed my hair"
Dutasteride can drastically reduce sebum production, leading to dryer hair and shedding. Alternating shampoos and periodic silica supplementation can improve hair quality and thickness.