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research Controversial Concepts in the Classification of Infundibular Squamous Cell Carcinoma and Tricholemmal Carcinoma

5 citations , May 2013 in “The American Journal of Dermatopathology”

The author now believes tricholemmal carcinoma is a rare type of infundibular squamous cell carcinoma and more research is needed on these tumors.

research Keratoacanthoma and Other Types of Squamous Cell Carcinoma with Crateriform Architecture: Classification and Identification

45 citations , February 2013 in “The Journal of Dermatology”

Keratoacanthoma and some squamous cell carcinomas are linked to hair follicles, while others are not.

research Stem Cell Quiescence Acts as a Tumor Suppressor in Squamous Tumors

66 citations , December 2013 in “Nature Cell Biology”

Inactive hair follicle stem cells help prevent skin cancer.

research Viewpoint 4

1 citations , April 2008 in “Experimental Dermatology”

Hidradenitis suppurativa may mainly affect vellus hair follicles, not terminal ones.

research Inverted Follicular Keratosis of the Lower Eyelid: A Diagnostic Conundrum

September 2025 in “Annals of Plastic Surgery”

Inverted follicular keratosis on the eyelid can be cured with surgery and has a great prognosis.

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community I think I’ve finally found the reason for my hair loss

in Chat 98 upvotes 1 year ago

The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 1 year ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 2 years ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Is Finasteride the only way to reduce scalp DHT?

in Chat 28 upvotes 2 months ago

A 24-year-old male experienced side effects like low libido and ED after starting finasteride post-hair transplant and is seeking alternatives to reduce scalp DHT. Suggestions include topical finasteride, Xpecia, DHT-reducing shampoos, and switching to dutasteride, with some users reporting fewer side effects with these alternatives.

community Quote from Pelage (PP-405) Spokesperson...

in Research/Science 121 upvotes 3 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

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