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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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      natural substance from Neem tree with medicinal and pesticidal properties

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 2 years ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community Minoxidil is a 5ar inhibitor according to research

      in Research/Science  146 upvotes 5 months ago
      Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

      community Can aromatase inhibitors make dutasteride/finasteride useless?

      in Finasteride/Dutasteride  9 upvotes 1 year ago
      The conversation discusses using aromatase inhibitors with dutasteride or finasteride for hair loss, which can prevent testosterone from turning into estrogen but may lead to increased DHT and potentially make finasteride less effective. There's concern about proper dosing and side effects like gynecomastia and emotional changes.