research Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin 5 citations , May 2023 in “Frontiers in Cell and Developmental Biology” Integrin α6 helps identify different neural crest cell types in the skin.
research Hair Follicular Expression of Integrin Alpha-6 Subunit and p63 in Hair Loss January 2008 in “Journal of Clinical Dermatology” Integrin alpha-6 and p63 proteins may play a role in hair loss and are important for hair growth and maintenance.
research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability 28 citations , January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche 6 citations , May 2013 in “PloS one” The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
research Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation 8 citations , April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.
learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss