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GlossaryIntercellular Adhesion Molecule 1

protein aiding white blood cells in adhering to vessel walls

Intercellular Adhesion Molecule 1 (ICAM-1), also known as CD54, is a protein found on the surface of cells that plays a crucial role in the immune response. It helps white blood cells stick to and move through the walls of blood vessels to reach sites of infection or injury. This molecule is important in inflammation and can be involved in various diseases, including autoimmune disorders and cancer.

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research Intercellular Adhesion Molecule-1 and Hair Follicle Regression

29 citations , April 2000 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

ICAM-1 helps regulate hair growth cycles and skin remodeling.

Oral Contraceptive Pill Treatment Alters Gene Expression of Inflammatory Markers in Polycystic Ovary Syndrome Women

research Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women

2 citations , February 2023 in “BMC women's health”

Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.

research Localization of intercellular adhesion molecule-1 in middle ear cholesteatoma

13 citations , November 1995 in “European Archives of Oto-Rhino-Laryngology”

research Detection of Functionally Active Melanocortin Receptors and Evidence for an Immunoregulatory Activity of α-Melanocyte-Stimulating Hormone in Human Dermal Papilla Cells

60 citations , August 2005 in “Endocrinology”

αMSH may help regulate immune responses in hair follicles and its disruption could lead to hair loss.

research Expression of melanocortin receptors on cutaneous fibroblastic cells – collagen and beyond

1 citations , January 2005 in “Experimental Dermatology”

MC-1R in skin cells may influence inflammation and collagen production.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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