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GlossaryInterleukin-1 alpha

promotes inflammation and influences hair follicle biology

Interleukin-1 alpha (IL-1α) is a type of protein known as a cytokine, which plays a crucial role in the body's immune response by promoting inflammation. It is involved in various cellular activities, including cell proliferation, differentiation, and apoptosis. In the context of hair and alopecia, IL-1α can influence hair follicle biology and has been implicated in inflammatory conditions that may lead to hair loss.

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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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research Effects of Acanthus Ebracteatus Vahl Extract and Verbascoside on Human Dermal Papilla and Murine Macrophage

7 citations , January 2022 in “Scientific Reports”

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

research Causal Relationship Between Inflammatory Cytokines and Polycystic Ovary Syndrome: A Bidirectional Mendelian Randomization Study

12 citations , November 2024 in “Journal of Ovarian Research”

Certain inflammatory factors may increase or decrease the risk of developing PCOS.

research Pro-Inflammatory Cytokine Cascade in Human Plucked Hair

September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.

research Effect of Ficus Carica Leaf Extract on the Gene Expression of Selected Factors in HaCaT Cells

16 citations , April 2017 in “Journal of Cosmetic Dermatology”

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

research Evaluating Antiinflammatory and Antiandrogenic Effects of Garden Cress (Lepidium Sativum L.) in HaCaT Cells

5 citations , June 2018 in “Records of Natural Products”

Garden cress extract may help treat skin inflammation and androgen-related disorders.

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community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 15 upvotes 1 year ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 442 upvotes 4 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.