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research Cutaneous manifestations associated with substance use disorders

April 2025 in “JAAD reviews.”

Substance use disorder (SUD) is a significant public health issue with frequent and varied cutaneous manifestations that can indicate specific substance use or administration methods. Intravenous drug use is often linked to vascular, lymphatic complications, and skin infections, while other lesions may result from inflammatory or foreign body responses. Dermatologists play a crucial role in identifying these skin signs, which can suggest undisclosed substance misuse, and should collaborate with addiction specialists for comprehensive care. A multidisciplinary dermatopsychiatric approach is recommended to enhance patient outcomes, and its effectiveness should be regularly evaluated.

research Idiopathic CD4+ T-Lymphocytopenia

27 citations , September 1992 in “The Lancet”

ICL is a condition with low CD4+ T cells like AIDS but not caused by HIV, and normal CD4+ T cell counts may vary between men and women.

research Telogen Effluvium as a Clinical Presentation of Human Immunodeficiency Virus Infection

5 citations , April 2002 in “The American Journal of Medicine”

Hair loss can be an early sign of HIV infection.

research Pharmacokinetics, Toxicity, and Activity of Intravenous Dextran Sulfate in Human Immunodeficiency Virus Infection

142 citations , December 1991 in “Antimicrobial Agents and Chemotherapy”

Dextran sulfate was found to be toxic and ineffective for treating HIV.

research Telogen Effluvium and Minoxidil

19 citations , September 1989 in “Journal of The American Academy of Dermatology”

Minoxidil treatment may cause hair loss.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 4 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Sublingual Minoxidil - Cure to Hairloss?

in Minoxidil 583 upvotes 2 years ago

The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.

community When are we getting a cure to hair loss?

in Chat 2 years ago

Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

community Tressless When They See Verteporfin Results

in Transplants 182 upvotes 2 years ago

The conversation discusses the potential of Verteporfin, an FDA-approved drug, for hair loss treatment, particularly in combination with microneedling or PRP. Users express hope and curiosity about its application, while some remain cautious due to the need for more extensive testing.

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